The published version of our work on dormancy: stromal TGFβ1 upregulates neuropilin-2 in disseminated tumour cells in the lung, driving their escape from dormancy and the outgrowth of metastasis. Understanding what wakes these cells up is one of the central questions in metastasis.
Recalde-Percaz L, de la Guia-Lopez I, Linzoain-Agos P, et al. Neuropilin-2 upregulation by stromal TGFβ1 induces lung disseminated tumor cells dormancy escape and promotes metastasis outgrowth. Neoplasia. 2025 Oct;68:101220.