A review on how CRISPR-based genetic screens are being used to take apart the pathways that cancer cells use to survive stress — and what that tells us about where the exploitable vulnerabilities are.
Mokhles F, Moosavi MA, Gutierrez-Uzquiza A, Velasco G, Li M, Cordani M. Unraveling stress-adaptation pathways in cancer: functional dissection through CRISPR-based genetic screens. Cancer Letters. 2026;644:218246.